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A 38-site, patient-randomised, two-arm superiority trial comparing, in parallel groups, open urethroplasty (experimental) with endoscopic urethrotomy (control) for men with recurrent bulbar urethral stricture Objectives: To assess benefit, harms and cost-effectiveness of open urethroplasty compared with endoscopic urethrotomy as treatment for recurrent urethral stricture in men To assess benefit, harms and cost-effectiveness of open urethroplasty compared with endoscopic urethrotomy as treatment for recurrent urethral stricture in men May 3, 2021 · To assess the relative cost-effectiveness of open urethroplasty and endoscopic urethrotomy as treatment for recurrent urethral stricture in men Jan 12, 2021 · Set in the UK National Health Service with recruitment from 38 hospital sites, a randomised controlled trial of open urethroplasty and endoscopic urethrotomy with 6-monthly follow-up over 24 months was conducted To assess benefit, harms and cost-effectiveness of open urethroplasty compared with endoscopic urethrotomy as treatment for recurrent urethral stricture in men There was no evidence of a difference regarding voiding symptoms in men with recurrent bulbar urethral stricture randomised to urethrotomy or urethroplasty However, men allocated to urethroplasty had fewer reinterventions than those allocated to Dec 30, 2015 · The open urethroplasty versus endoscopic urethrotomy (OPEN) trial aims to better guide the choice of treatment for men with recurrent urethral strictures by comparing benefit over 2 years in terms of symptom control and need for further treatment Oct 1, 2020 · Urethral stricture affects 0 9% of men Initial treatment is urethrotomy Approximately, half of the strictures recur within 4 yr Options for further…The optimal treatment for short-segment strictures remains debated between minimally invasive direct vision internal urethrotomy (DVIU) and definitive open urethroplasty This study aimed to compare the functional outcomes, recurrence rates and complications between DVIU and urethroplasty in short-segment anterior urethral strictures
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